Isogeometric analysis (IGA) was first presented by T. Hughes (2005). Although interest has grown exponentially in academia in recent years, in the automotive industry the level of integration is still low. Recent developments in IGA using trimmed NURBS [1] show great potential for the simulation of industrial components. They allow the use of trimmed multi-patch B-Rep models [2], which are extensively used in industrial CAD design. In addition, widely used commercial software in the automotive industry are increasing their IGA capabilities, such as ANSA pre-processor and LS-DYNA numerical solver. This opens the possibility to integrate IGA in the current automotive workflows with either pure-IGA or hybrid FEA-IGA models. This work presents some of the findings done in an Industrial PhD between IDIADA and UPC that aims to focus on the key points that remain to be addressed for a wide adoption of IGA in the automotive industry. Such as, modelling guidelines, modelling of component features, cross-talk effect due to trimming technique and crack modelling with IGA. The final objective is to establish an industrial validation for crashworthiness CAE analysis for full vehicle.